Analytical Data
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Gene name
MSI2
- Application
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Alternative Names
RNA-binding protein Musashi homolog 2; MSI2; Homo sapiens; Human; Musashi-2; RNA-binding
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Species
Human
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Source
E. coli
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Tag
Strep;His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96DH6-1
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Expression Region
Q17-K111
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Protein Length
Partial
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MSI2, or Musashi RNA-binding protein 2, is a member of the Musashi family of proteins that play critical roles in regulating gene expression and stem cell maintenance through their interactions with RNA. Research on MSI2 has gained traction due to its significant involvement in various biological processes, including cell differentiation, proliferation, and development. It is particularly noted for its function in stem cells and cancer biology, as MSI2 is often overexpressed in several malignancies, contributing to tumorigenesis and poor prognosis. This interest is further fueled by its regulatory role in mRNA stability and translation, impacting pathways associated with the cell cycle and apoptosis. Understanding MSI2's mechanisms can provide insights into its potential as a therapeutic target, particularly in cancer where aberrant expression patterns are observed. As such, exploring MSI2’s roles and interactions within cellular contexts not only enhances knowledge of fundamental biological processes but also holds promise for developing innovative treatment strategies for diseases linked to dysregulated RNA-binding proteins.
