Cat: IPD-X28597

Recombinant Human GPR158 Protein (HEK293)

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Analytical Data

  • Gene name

    GPR158

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    KIAA1136

  • Species

    Human

  • Source

    HEK293

  • Tag

    Tag Free

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q5T848

  • Expression Region

    M1-E775

  • Protein Length

    Partial

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

GPR158 is a G protein-coupled receptor (GPCR) that plays a significant role in various neurological processes and mental disorders. It is predominantly expressed in the brain, particularly in areas associated with cognition and emotion regulation. The study of GPR158 has garnered attention due to its potential implications in conditions such as depression, anxiety, and schizophrenia. Recent research indicates that GPR158 is involved in modulating synaptic transmission and neuronal plasticity, which are crucial for learning and memory. The receptor's unique structure and its interactions with different signaling pathways offer insights into its function and potential as a therapeutic target. Moreover, the development of recombinant GPR158 proteins allows researchers to investigate its biochemical properties, ligand binding, and downstream signaling mechanisms in detail. Understanding the role of GPR158 in the central nervous system could lead to novel interventions for mental health disorders, making it a significant focus in neuroscience and pharmacology research. As such, the characterization of GPR158 recombinant proteins is essential for elucidating their biological functions and exploring their potential in drug development.

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