Analytical Data
-
基因名
ABCB10
- Application
-
种属
Human
-
表达系统
HEK293
-
标签
His;Flag
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9NRK6
-
表达区间
A152-A738, N229A, N407A
-
蛋白长度
Partial
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ABCB10, a member of the ATP-binding cassette (ABC) transporter family, has garnered significant interest in recent years due to its critical role in cellular processes, particularly in the transport of various substrates across cellular membranes. This protein is predominantly expressed in hematopoietic tissues and has been implicated in iron metabolism, affecting erythropoiesis and overall cellular iron homeostasis. Aberrant expression or mutations in ABCB10 have been associated with various hematological disorders, including anemia and other blood-related pathologies. Furthermore, emerging studies suggest that ABCB10 may play a role in drug resistance mechanisms in cancer cells, highlighting its potential impact on therapeutic efficacy. Investigating the structure and function of ABCB10, particularly through recombinant protein strategies, can provide insights into its mechanistic roles and regulatory pathways. Understanding ABCB10's function could pave the way for novel therapeutic approaches targeting iron-related disorders and improving treatment responses in oncology.
