Analytical Data
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Gene name
ZEB2
- Application
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Alternative Names
KIAA0569; SIP1; ZFHX1B; ZFX1B
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Species
Human
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Source
E. coli
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Tag
Tag Free
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O60315-1
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Expression Region
S647-S705
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Protein Length
Partial
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZEB2 (Zinc Finger E-Box Binding Homeobox 2) is a transcription factor that belongs to the ZF-Herpesvirus family of proteins and is primarily involved in the regulation of epithelial-to-mesenchymal transition (EMT), a crucial process in embryonic development and tumor progression. Dysregulation of ZEB2 has been implicated in various cancers, particularly in promoting invasiveness and metastasis, making it a significant target for cancer research. Moreover, ZEB2 is also essential for neural crest development and has been linked to several developmental disorders, including Waardenburg syndrome. The study of ZEB2 recombinant proteins facilitates understanding its structural and functional properties, allowing researchers to explore its role in different biological contexts. By producing ZEB2 in a recombinant form, it becomes possible to analyze its interactions with other proteins, DNA binding characteristics, and modulation of downstream signaling pathways. Moreover, recombinant ZEB2 can be utilized in high-throughput screening assays for identifying small molecules that can potentially inhibit its function, presenting a promising avenue for therapeutic intervention in ZEB2-related diseases. Overall, the research on ZEB2 recombinant proteins not only enhances our comprehension of its pivotal role in cellular processes but also opens up new strategies for targeted therapies in oncology and developmental biology.
