Analytical Data
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基因名
ZEB2
- Application
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别名
KIAA0569; SIP1; ZFHX1B; ZFX1B
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种属
Human
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表达系统
E. coli
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标签
Tag Free
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O60315-1
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表达区间
S647-S705
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蛋白长度
Partial
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZEB2 (Zinc Finger E-Box Binding Homeobox 2) is a transcription factor that belongs to the ZF-Herpesvirus family of proteins and is primarily involved in the regulation of epithelial-to-mesenchymal transition (EMT), a crucial process in embryonic development and tumor progression. Dysregulation of ZEB2 has been implicated in various cancers, particularly in promoting invasiveness and metastasis, making it a significant target for cancer research. Moreover, ZEB2 is also essential for neural crest development and has been linked to several developmental disorders, including Waardenburg syndrome. The study of ZEB2 recombinant proteins facilitates understanding its structural and functional properties, allowing researchers to explore its role in different biological contexts. By producing ZEB2 in a recombinant form, it becomes possible to analyze its interactions with other proteins, DNA binding characteristics, and modulation of downstream signaling pathways. Moreover, recombinant ZEB2 can be utilized in high-throughput screening assays for identifying small molecules that can potentially inhibit its function, presenting a promising avenue for therapeutic intervention in ZEB2-related diseases. Overall, the research on ZEB2 recombinant proteins not only enhances our comprehension of its pivotal role in cellular processes but also opens up new strategies for targeted therapies in oncology and developmental biology.
