Analytical Data
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Gene name
GPR52
- Application
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Alternative Names
G-protein coupled receptor 52; GPR52; Homo sapiens; Human; G-protein coupled receptor; Receptor; Transducer
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Species
Human
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Source
HEK293
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Tag
His;Flag
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y2T5
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Expression Region
G17-K235, R262-M340, A130W, A264L, W278Q, C314P, S318A, N321D, V323T
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Protein Length
Partial
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GPR52, a member of the G protein-coupled receptor (GPCR) family, has garnered attention in recent years due to its potential role in neuropsychiatric disorders. As an orphan receptor, its endogenous ligand and physiological functions remain largely unexplored, making it a target of interest for researchers aiming to understand its implications in conditions like schizophrenia and mood disorders. Recent studies suggest that GPR52 may influence dopaminergic pathways and glutamatergic signaling, vital processes in brain function and behavior. The ability to produce recombinantly expressed GPR52 protein has opened avenues for in-depth analysis of its biochemical properties, receptor signaling mechanisms, and interaction with potential ligands. Such studies can provide critical insights into the receptor's role in the central nervous system, paving the way for the development of novel therapeutic strategies aimed at treating various psychiatric conditions linked to GPCR dysregulation. Enhanced understanding of GPR52 could lead to breakthroughs in drug discovery and offer hope for improved management of complex neuropsychiatric disorders.
