Cat: IPD-X28488

Recombinant Human KCC1 Protein (HEK293),His & Flag

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Analytical Data

  • 基因名

    KCC1

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    KCC1

  • 种属

    Human

  • 表达系统

    HEK293

  • 标签

    His;MBP;Flag

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q9UP95-1

  • 表达区间

    M1-S1085

  • 蛋白长度

    Full Length of Isoform-1

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

KCC1, or the potassium chloride co-transporter 1, is a vital member of the solute carrier (SLC) superfamily, playing a crucial role in maintaining cell volume, pH balance, and ion homeostasis. It is predominantly expressed in various tissues, including the brain, kidney, and epithelial cells. Dysregulation of KCC1 function has been implicated in several pathological conditions, such as hypertension, cerebral edema, and neurological disorders. Consequently, the study of recombinant KCC1 protein has gained significant attention, focusing on its functional characterization, structural biology, and potential therapeutic implications. Researchers employ various molecular biology techniques to express and purify KCC1 in heterologous systems, allowing for in-depth studies on its transport mechanisms and regulatory pathways. Understanding the structure-function relationship of KCC1 is critical to deciphering its role in physiological processes and its involvement in disease states, which may pave the way for the development of novel pharmacological interventions targeting this transporter. As the demand for effective treatments for related disorders increases, the study of KCC1 and its recombinant protein forms stands to contribute valuable insights into both basic science and clinical applications.

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Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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