Cat: IPD-X28467

Recombinant Human ASCT2 Protein (Baculovirus)

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Analytical Data

  • 基因名

    ASCT2

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    ASCT2; M7V1; RDR; RDRC

  • 种属

    Human

  • 表达系统

    Baculovirus

  • 标签

    Tag Free

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q15758-1

  • 表达区间

    M1-M541

  • 蛋白长度

    Full Length of Isoform-1

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

ASCT2 (Alanine-Serine-Cysteine Transporter 2) is a key member of the solute carrier (SLC) family responsible for the transport of neutral amino acids across cellular membranes. Its significance lies in its role in maintaining amino acid homeostasis, which is crucial for various physiological processes, including protein synthesis, neurotransmission, and metabolic regulation. Dysregulation of ASCT2 has been implicated in several pathological conditions, including cancer, where it can contribute to tumor growth and survival by facilitating the uptake of essential amino acids. Given its potential as a therapeutic target, research into ASCT2 recombinant proteins has gained momentum, aiming to elucidate its transport mechanisms and substrate specificity. The production of recombinant ASCT2 proteins in suitable expression systems allows for detailed biochemical and biophysical characterization, enabling scientists to explore the structural aspects that govern its function. Additionally, understanding ASCT2’s interaction with small molecules and potential inhibitors can pave the way for the development of innovative strategies to modulate its activity in diseases. Overall, the study of ASCT2 recombinant proteins is an essential step towards understanding the role of amino acid transporters in health and disease, potentially leading to novel therapeutic interventions.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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