Cat: IPD-X28457

Recombinant Human RLBP1 Protein,His

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Analytical Data

  • 基因名

    RLBP1

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    CRALBP; Cellular retinaldehyde-binding protein

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 95% as determined by SDS-PAGE.

  • 蛋白编号

    P12271

  • 表达区间

    Met1~ Phe317

  • 分子量

    40kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

RLBP1 (Retinal Pigment Epithelium-Bound Protein 1) is a crucial protein involved in the visual cycle and phototransduction, primarily localized in the retinal pigment epithelium (RPE). Mutations in the RLBP1 gene can lead to various retinal disorders, including retinitis pigmentosa and fundus flavimaculatus, highlighting its importance in maintaining retinal health and function. The study of RLBP1 recombinant proteins has gained significant attention as it provides valuable insights into the protein’s structural and functional properties. By expressing RLBP1 in heterologous systems, researchers aim to investigate its binding affinities, interactions with other retinal proteins, and its role in the transport of retinoids—molecules essential for vision. Furthermore, understanding the biochemical pathways involving RLBP1 may pave the way for developing therapeutic strategies for retinal diseases linked to RLBP1 dysfunction. Recombinant RLBP1 serves as a powerful tool for elucidating the mechanistic details underlying its activity and potential as a target for drug discovery in ophthalmology. The ongoing investigations into RLBP1 recombinant protein not only shed light on the basic biology of retinal function but also hold promise for innovative treatments for patients suffering from retinopathies related to this vital protein.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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