Analytical Data
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Gene name
NPY1R
- Application
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Alternative Names
NPYR; NPYY1
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Species
Human
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Source
Baculovirus
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Tag
His;Flag
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P25929
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Expression Region
N2-R241, D250-D358, F129W
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Protein Length
Partial
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NPY1R (Neuropeptide Y receptor Y1) is a crucial G-protein-coupled receptor that plays a significant role in various physiological processes, including appetite regulation, stress response, and circadian rhythms. Research into NPY1R has expanded due to its implications in metabolic disorders, anxiety, and depression. The receptor is activated by neuropeptide Y (NPY) and peptide YY (PYY), which are involved in the modulation of food intake and energy homeostasis. Understanding NPY1R's functioning at a molecular level can provide insights into the pathophysiology of obesity and anxiety-related disorders, as dysregulation of this receptor has been linked to increased food consumption and anxiety behaviors. The development of NPY1R recombinant proteins has allowed for detailed studies on receptor binding, signaling pathways, and potential therapeutic applications. Moreover, the production of these proteins facilitates assays to screen for small molecules that can modulate NPY1R activity, offering potential avenues for drug discovery aimed at treating conditions such as obesity and depression. As research progresses, elucidating the structural and functional characteristics of NPY1R will be vital for the advancement of targeted therapies that can selectively influence its activity while minimizing side effects. Overall, the study of NPY1R recombinant proteins is essential for understanding receptor biology and developing effective interventions for related health issues.
