Analytical Data
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基因名
GRM1
- Application
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别名
GPRC1A; GRM1A; MGLUR1; MGLUR1A; mGluR1
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q13255
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表达区间
Ser165~Glu592
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分子量
52kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GRM1, or Glutamate Receptor Metabotropic 1, is a member of the metabotropic glutamate receptor family, which plays a crucial role in modulating synaptic transmission and plasticity in the central nervous system. The study of GRM1 has garnered significant attention in recent years due to its involvement in various neurological disorders, including schizophrenia, neurodegeneration, and mood disorders. Researchers have been particularly interested in GRM1 recombinant proteins to elucidate its functional mechanisms and potential as a therapeutic target. The development of GRM1 recombinant proteins allows for detailed investigations into receptor signaling pathways, ligand-binding characteristics, and interaction with other cellular components. Additionally, these proteins can be utilized in high-throughput screening for potential pharmacological agents that could modulate GRM1 activity, offering insights into novel treatment strategies for associated disorders. Understanding the structure and dynamics of GRM1 through these recombinant proteins could pave the way for advancements in drug discovery, highlighting its significance in neuroscience research.
