Analytical Data
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基因名
GNA14
- Application
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别名
uanine nucleotide-binding protein subunit alpha-14; G alpha-14; G-protein subunit alpha-14; GNA14
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种属
Human
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表达系统
E. coli
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标签
GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O95837
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表达区间
M1-V355
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蛋白长度
Full Length
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GNA14, a member of the G-protein coupled receptor (GPCR) signaling pathway, plays a pivotal role in various physiological processes, including vascular development, cell signaling, and the regulation of hormonal responses. Its function is crucial in mediating intracellular signaling cascades in response to extracellular stimuli, making it a significant target for therapeutic interventions in various diseases, including cancer and metabolic disorders. The recombinant protein of GNA14 has been increasingly studied to understand its structure-function relationships and biological activities, which can provide insights into its role in signaling pathways and potential as a drug target. The ability to produce GNA14 as a recombinant protein allows for advanced biochemical assays and structural analyses, facilitating the exploration of its interactions with other proteins and small molecules. This research is essential for uncovering the mechanistic details of GNA14-mediated signaling and for identifying novel therapeutic strategies to modulate its activity in disease contexts. Understanding GNA14's role at the molecular level not only enhances our knowledge of GPCR functions but also drives the development of innovative pharmacological interventions, expanding the prospects for targeted therapies. Overall, the study of GNA14 recombinant protein is crucial for translating basic research findings into clinical applications, thereby addressing urgent therapeutic needs in various health conditions.











