Analytical Data
-
基因名
TAFA2/FAM19A2
-
简介
The FAM19A2 protein plays a key role as a neurotrophic factor, actively promoting neuronal survival and various neurobiological functions. Its involvement is shown to have a critical impact on the maintenance and health of neurons, underscoring its potential significance in supporting neurological health. TAFA2/FAM19A2 Protein, Human is the recombinant human-derived TAFA2/FAM19A2 protein, expressed by E. coli , with tag free.
- Application
-
生物活性
1. The biological activity is determined by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons. rHuTAFA-2; immobilized at 6-24 μg/mL on a 96 well plate; is able to significantly enhance neurite outgrowth. 2. Measured in a cell proliferation assay using SH-SY5Y human neuroblastoma cells. The ED50 this effect is 1.455-3.659 μg/mL, corresponding to a specific activity is > 273.30 units/mg. Measured in a cell proliferation assay using SH-SY5Y human neuroblastoma cells. The ED50 for this effect is 3.659 μg/ml, corresponding to a specific activity is 273.30 units/mg.
-
别名
Chemokine-like protein TAFA-2; TAFA-2; FAM19A2
-
种属
Human
-
表达系统
E. coli
-
标签
Tag Free
-
纯度
Greater than 95% as determined by SDS-PAGE.
-
蛋白编号
Q8N3H0-1
-
表达区间
A31-H131
-
蛋白长度
Full Length of Isoform-1 Mature Protein
-
分子量
11-15 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TAFA2, also known as FAM19A2, is a member of the TAFA family of proteins, which are characterized by their unique structure and potential biological roles in immune response and inflammation. Research has indicated that TAFA2 is associated with various physiological processes, particularly in the nervous and immune systems. Its expression is observed in various tissues, and dysregulation of TAFA2 has been implicated in several pathological conditions, including neurological disorders and cancer. The recombinant form of TAFA2/FAM19A2 allows researchers to study its functional properties and interactions in vitro. Investigating the structure-function relationships of this protein enhances our understanding of its role in cellular signaling and immune modulation. By utilizing recombinant technology, scientists aim to elucidate the mechanisms through which TAFA2 influences inflammatory responses, thereby paving the way for potential therapeutic applications in diseases where its pathway is disturbed. Overall, the exploration of TAFA2/FAM19A2 as a recombinant protein holds promise for unveiling its significance in health and disease, providing insights that could lead to innovative treatments and biomarker development.
