Analytical Data
-
基因名
NPDC-1
-
简介
NPDC-1 protein critically hinders oncogenic transformation in neural and non-neural cells, suppressing neural cell proliferation. Its multifaceted impact extends to transcriptional regulation, emphasizing its role as a regulator with implications for mitigating oncogenic processes and modulating cellular proliferation in diverse cell systems. NPDC-1 Protein, Human (HEK293, His) is the recombinant human-derived NPDC-1 protein, expressed by HEK293 , with C-6*His labeled tag.
- Application
-
别名
Neural proliferation differentiation and control protein 1; NPDC-1; NPDC1; RP11-229P13.1; CAB; CAB-1; CAB1
-
种属
Human
-
表达系统
HEK293
-
标签
C-6*His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9NQX5
-
表达区间
G35-D181
-
蛋白长度
Partial
-
分子量
28-35 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NPDC-1 (Neuron-Precursor-Cell-Death) is a protein that has gained significant attention in recent years due to its potential role in neurodevelopment and neurodegenerative diseases. Originally identified in neuronal precursor cells, NPDC-1 is thought to be involved in regulating cell survival and differentiation during the early stages of brain development. Research indicates that alterations in NPDC-1 expression may be linked to conditions such as Alzheimer's disease and other neurodegenerative disorders, suggesting that it plays a critical role in neuronal health. Recent studies have focused on the structural and functional properties of NPDC-1, exploring its interactions with various signaling pathways and molecular partners. Understanding NPDC-1's mechanisms could provide valuable insights into the underlying biological processes that lead to neuronal loss and impaired function. As researchers develop recombinant NPDC-1 proteins for experimental use, they aim to clarify its biological roles and therapeutic potential, paving the way for innovative strategies to combat neurodegeneration. The investigation of NPDC-1 not only enhances our understanding of cellular processes in the nervous system but also underscores the importance of molecular targets in the development of future treatments for neurological disorders.
