Analytical Data
-
基因名
MTCP1
-
简介
The MTCP1 protein plays a crucial role in promoting the phosphorylation and activation of AKT1 and AKT2, two key members of the AKT family. It does this through specific interactions with AKT1 and AKT2, primarily through their PH (pleckstrin homology) domains. MTCP1 Protein, Human is the recombinant human-derived MTCP1 protein, expressed by E. coli , with tag free.
- Application
-
别名
MTCP1; Protein p13 MTCP-1; p13MTCP1; Mature T-cell proliferation-1 type B1; MTCP-1 type B1
-
种属
Human
-
表达系统
E. coli
-
标签
Tag Free
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P56278
-
表达区间
M1-D107
-
蛋白长度
Full Length
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of MTCP1 (Mammalian T-cell leukemia virus type 1 (MTLV-1) regulatory protein) has gained significant importance due to its potential implications in cancer biology and immunology. MTCP1 is encoded by the human T-cell leukemia virus type 1 (HTLV-1), which is known to cause adult T-cell leukemia/lymphoma (ATLL). The presence of MTCP1 has been linked to the transformation of T-cells, influencing their proliferation and survival, and contributing to the pathogenesis of hematological malignancies. Understanding the structure and function of MTCP1 is crucial, as it may offer insights into viral oncogenesis and immune evasion mechanisms. Previous research has shown that MTCP1 can interact with various cellular proteins and modulate signaling pathways, particularly those related to apoptosis and cell cycle regulation. By investigating the recombinant expression of MTCP1, researchers aim to elucidate its functional roles at a molecular level, which could ultimately lead to the development of targeted therapies for HTLV-1-associated diseases. The recombinant protein serves as a valuable tool in both basic and applied research, enabling the study of its interaction with host factors and its effect on T-cell behavior. Overall, research on MTCP1 is poised to contribute to a deeper understanding of viral infections and their links to cancer, thereby opening avenues for innovative therapeutic strategies.
