Analytical Data
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基因名
CRISP-3
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简介
The CRISP-3 protein interacts with A1BG, indicating a molecular association with potential functional implications. This suggests that CRISP-3 may be involved in processes associated with or regulated by A1BG. The specific nature and significance of this interaction require further elucidation, emphasizing the need for additional investigation into the molecular mechanisms and biological consequences of the CRISP-3 and A1BG interaction. CRISP-3 Protein, Human (HEK293, His) is the recombinant human-derived CRISP-3 protein, expressed by HEK293 , with C-6*His labeled tag.
- Application
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别名
rHuCysteine-rich secretory protein 3/CRISP-3, His; Cysteine-Rich Secretory Protein 3; CRISP-3; Specific Granule Protein of 28 kDa; SGP28; CRISP3
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种属
Human
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表达系统
HEK293
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标签
C-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P54108
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表达区间
N21-Y245
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氨基酸序列
NEDKDPAFTALLTTQTQVQREIVNKHNELRRAVSPPARNMLKMEWNKEAAANAQKWANQCNYRHSNPKDRMTSLKCGENLYMSSASSSWSQAIQSWFDEYNDFDFGVGPKTPNAVVGHYTQVVWYSSYLVGCGNAYCPNQKVLKYYYVCQYCPAGNWANRLYVPYEQGAPCASCPDNCDDGLCTNGCKYEDLYSNCKSLKLTLTCKHQLVRDSCKASCNCSNSIY
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蛋白长度
Full Length of Mature Protein
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分子量
25-32 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CRISP-3, a member of the cysteine-rich secretory protein (CRISP) family, has garnered attention in the field of immunology and reproductive biology due to its distinct structural characteristics and functional roles. Originally identified in the context of the male reproductive system, CRISP-3 is believed to play a crucial role in sperm maturation and fertilization processes. The protein is secreted by the epithelial cells of the male genital tract and exhibits properties such as immunomodulation and potential involvement in cellular signaling pathways. Research has suggested that CRISP-3 may influence immune responses by modulating the activity of various immune cells, making it a candidate for exploring its therapeutic potential in conditions involving immune disorders or reproductive challenges. Additionally, understanding the mechanisms underlying CRISP-3 function could provide insights into male fertility and lead to the development of novel contraceptive methods or treatments for infertility. Given the growing interest in reproductive health, further studies are warranted to elucidate the molecular pathways associated with CRISP-3 and its implications for human health and disease.
