Analytical Data
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Gene name
KCT2
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简介
KCT2 protein, widely expressed across diverse tissues and cell types, indicates potential involvement in various physiological processes, highlighting its ubiquity within the biological landscape. KCT2 Protein, Human (HEK293, His) is the recombinant human-derived KCT2 protein, expressed by HEK293 , with C-His labeled tag.
- Application
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Alternative Names
Keratinocyte-associated transmembrane protein 2; KCT2; C5orf15; HTGN29
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Species
Human
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Source
HEK293
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Tag
C-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8NC54
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Expression Region
R50-D196
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Protein Length
Extracellular Domain
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Molecular Weight
33-47 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KCT2, a key protein implicated in various physiological and pathological processes, has garnered significant attention in the field of molecular biology and biochemistry. As a member of the KCT family, KCT2 plays a fundamental role in cellular signaling pathways and is involved in the regulation of ion transport, which is crucial for maintaining cellular homeostasis. Recent studies have demonstrated its association with several diseases, including neurological disorders and certain types of cancer, highlighting the importance of understanding its structure and function. Researchers have been focused on producing recombinant KCT2 proteins to investigate their biophysical properties, interaction with other cellular components, and potential therapeutic applications. By utilizing techniques such as protein engineering and expression systems, scientists aim to produce high yields of functional KCT2. This research not only contributes to the foundational knowledge of KCT2 but also opens avenues for developing targeted drugs and novel therapeutic strategies aimed at modulating its activity in disease contexts. Understanding KCT2’s molecular dynamics could thus provide valuable insights into its role in health and disease and pave the way for future biomedical advancements.
