Analytical Data
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基因名
IL-15R alpha & IL-15
- Application
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别名
CD215; IL15RA; CD215 antigen; IL-15 receptor subunit alpha; IL-15RA; IL-15R-alpha; interleukin 15 receptor; alpha; interleukin-15 receptor subunit alpha; MGC104179
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种属
Human
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表达系统
HEK293
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标签
C- Fc
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
Q13261
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表达区间
31-172aa
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分子量
42.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Interleukin-15 (IL-15) is a cytokine that plays a crucial role in the immune system, particularly in the proliferation and survival of T cells and natural killer (NK) cells. IL-15 exerts its effects through a specific receptor complex, and the IL-15 receptor alpha (IL-15Rα) is a key component of this complex. Research has shown that IL-15Rα not only serves as a binding partner for IL-15 but also contributes to its trans-presentation, enhancing the cytokine's activity. The recombinant protein forms of IL-15 and IL-15Rα have garnered significant interest for their potential therapeutic applications, particularly in cancer immunotherapy and the treatment of infectious diseases. By using recombinant technologies, scientists can produce these proteins in sufficient quantities for research and potential clinical use. Studies have indicated that the combination of IL-15 with its receptor can boost the immune response, leading to improved anti-tumor activity. Furthermore, understanding the structural and functional characteristics of IL-15Rα and IL-15 is vital for designing innovative therapeutic strategies that harness the power of the immune system. This research is paving the way for novel immunotherapeutic approaches that aim to enhance immune responses in various medical conditions, illustrating the importance of IL-15 and its receptor as integral components of the immune landscape.
