Analytical Data
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基因名
BVES
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简介
BVES protein is a cell adhesion molecule that is essential for the paracellular permeability barrier of tight junctions in epithelial cells. BVES Protein, Human (GST) is the recombinant human-derived BVES protein, expressed by E. coli , with N-GST labeled tag.
- Application
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别名
Blood vessel epicardial substance; hBVES; Popeye protein 1; BVES; POP1; POPDC1
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种属
Human
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表达系统
E. coli
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标签
N-GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NE79
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表达区间
M1-N36
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蛋白长度
Partial
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分子量
32.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of BVES (Blood Vessel Epicardial Substance) recombinant proteins has garnered significant attention due to their potential roles in cardiovascular health and development. BVES is a tight junction protein primarily expressed in endothelial cells, contributing to cellular adhesion and barrier function. Research indicates that BVES plays a pivotal role in maintaining vascular integrity and regulating angiogenesis, as well as influencing cellular signaling pathways associated with inflammation and repair mechanisms. Dysfunction or downregulation of BVES has been linked to various cardiovascular diseases, including hypertension and atherosclerosis. Furthermore, BVES expression has been shown to be modulated in response to stressors like hypoxia, suggesting its involvement in adaptive responses during disease progression. The production of recombinant BVES proteins allows for detailed investigations into their structural and functional properties, facilitating the exploration of their therapeutic potential. By understanding the molecular mechanisms underlying BVES function, researchers aim to develop innovative strategies for treating cardiovascular conditions, thereby enhancing patient outcomes and advancing the field of vascular biology. This research is essential not only for elucidating the fundamental biology of the cardiovascular system but also for identifying novel biomarkers and targets for pharmacological intervention.
