Analytical Data
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基因名
APLP-1
- Application
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别名
rHuAmyloid-like Protein 1, His; APLP-1; Amyloid-like Protein 1
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种属
Human
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表达系统
HEK293
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标签
C-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P51693
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表达区间
G42-P212
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蛋白长度
Partial
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分子量
18-20 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
APLP-1, or Amyloid Precursor-Like Protein 1, is a member of the amyloid precursor protein (APP) family, which has garnered significant attention due to its potential roles in neurobiology and pathology, particularly in relation to Alzheimer’s disease. The research focus on APLP-1 has intensified as it is believed to participate in several crucial biological processes, including neurodevelopment, synaptic function, and neuronal survival. Unlike its widely studied relative APP, which is implicated in amyloid plaque formation, APLP-1 is thought to have neuroprotective properties and may interact with cellular signaling pathways that promote cell survival and repair. Investigating APLP-1's structural characteristics, expression patterns, and functional roles in the brain is pivotal for understanding its contributions to neural health and disease. Furthermore, the study of APLP-1, especially in the context of its interaction with other proteins and its involvement in neurodegenerative processes, could illuminate new therapeutic targets and strategies for preventing or mitigating conditions like Alzheimer's disease. Efforts to produce recombinant APLP-1 proteins are essential for detailed biochemical analyses and functional studies, paving the way for enhanced comprehension of its mechanisms and impacts in neurological contexts. Overall, APLP-1 stands at the intersection of neurobiology and potential therapeutic avenues, making it a significant focus of current biomedical research.
