Recombinant Human FABP4 Protein，His

FABP4

FABP4 Protein, expressed mainly in adipocytes, crucially mediates lipid and retinoic acid transport. It binds long-chain fatty acids and retinoic acid, facilitating delivery to nuclear receptors. Functioning as a monomer and forming homodimers, FABP4 interacts with PPARG, contributing to its involvement in fatty acid metabolism and signaling pathways. FABP4 Protein, Human (His) is the recombinant human-derived FABP4 protein, expressed by E. coli , with N-6*His labeled tag.

SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

Measured in a cell proliferation assay using MCF-7 cells. The ED50 for this effect is 65.15 ng/mL, corresponding to a specific activity is 1.535×10^4 units/mg. Measured in a cell proliferation assay using MCF-7 cells. The ED50 for this effect is 65.15 ng/mL, corresponding to a specific activity is 1.535×10^4 units/mg.

rHuFatty acid-binding protein adipocyte/FABP4, His; Fatty Acid-Binding Protein Adipocyte; Adipocyte Lipid-Binding Protein; ALBP; Adipocyte-Type Fatty Acid-Binding Protein; A-FABP; AFABP; Fatty Acid-Binding Protein 4

Human

E. coli

N-6*His

Greater than 95% as determined by SDS-PAGE.

P15090

C2-A132

Full Length of Mature Protein

16 kDa

< 1.0 EU per μg protein as determined by the LAL method.

Freeze-dried powder

PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.