Analytical Data
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基因名
Chemotaxis inhibitory
- Application
-
别名
CHIPS
-
种属
Staphylococcus aureus
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6GFB3
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表达区间
29-149aa
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分子量
21.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Chemotaxis inhibitory protein (Chips) is a critical protein that plays a significant role in modulating the immune response, particularly in the context of infections and inflammation. Originally identified in the context of bacterial pathogenesis, Chips are known to inhibit the movement (chemotaxis) of immune cells towards the site of infection by interfering with chemokine signaling pathways. This action can be both beneficial and detrimental; while it may prevent excessive inflammation and tissue damage during an infection, it can also hinder effective immune responses, allowing pathogens to persist. Recent studies have highlighted the potential of recombinant Chips as therapeutic agents in managing inflammatory diseases and promoting better immune regulation. By understanding the structure-function relationship of these proteins, researchers aim to develop targeted therapies that could enhance immune responses to infections or modulate inflammation in autoimmune conditions. Additionally, the applications of recombinant technology in producing these proteins have opened new avenues for drug development and interventions in immune-related disorders, making the study of Chemotaxis inhibitory proteins a rapidly expanding field with promising implications for clinical therapeutics.












