Analytical Data
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基因名
PLXNA1
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简介
PLXNA1 protein serves as a co-receptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D, achieving cytoskeletal remodeling and signaling through three types of signaling proteins. PLXNA1 Protein, Human (His) is the recombinant human-derived PLXNA1 protein, expressed by E. coli , with N-His labeled tag.
- Application
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别名
PLXNA1; NOV; PLXN1; Plexin-A1; Semaphorin receptor NOV
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UIW2
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表达区间
L986-L1152
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蛋白长度
Partial
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PLXNA1 (Plexin A1) is a receptor involved in guiding neuronal development and maintaining physiological processes through its interaction with semaphorins, a class of secreted signaling molecules. As a member of the plexin family, PLXNA1 plays a crucial role in the regulation of axon guidance, neuronal patterning, and the immune response. Research has indicated its significant involvement in various physiological and pathological conditions, including cancer metastasis, neurological disorders, and cardiovascular diseases. The study of PLXNA1 recombinant proteins serves as a valuable tool for elucidating the intricacies of its signaling pathways and biological functions. Utilizing recombinant PLXNA1 can facilitate in-depth investigations into its receptor activity, ligand binding, and downstream signaling mechanisms. Such studies may not only provide insights into fundamental biological processes but also open avenues for therapeutic interventions targeting PLXNA1 in diseases characterized by aberrant semaphorin signaling. Given the growing recognition of the importance of plexins in disease, the exploration of PLXNA1 recombinant proteins is essential for advancing our understanding of its role in health and disease management.
