Analytical Data
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Gene name
PLA2G2D
- Application
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Alternative Names
PLA2IIDPhosphatidylcholine 2-acylhydrolase 2DSecretory-type PLA, stroma-associated homolog
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Species
Human
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Source
E. coli
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Tag
N- His-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UNK4
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Expression Region
22-145aa
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Molecular Weight
30.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PLA2G2D, a member of the phospholipase A2 (PLA2) family, has garnered significant attention due to its potential roles in various physiological and pathological processes. Structurally, PLA2G2D is an enzyme that catalyzes the hydrolysis of phospholipids, leading to the generation of lysolipids and free fatty acids, which are crucial for cell signaling, membrane dynamics, and inflammation. Research has indicated that PLA2G2D might play a role in immune responses, particularly in modulating the activity of immune cells and influencing the progression of inflammatory diseases. Its expression has been linked to cancer and other diseases, making it a potential therapeutic target. The generation of recombinant PLA2G2D proteins has facilitated the exploration of their structure-function relationships, as well as their interactions with various biological substrates. These studies are vital for understanding the enzyme's biological significance and its potential as a diagnostic or therapeutic biomarker in diseases. Moreover, characterizing PLA2G2D can also provide insights into the broader functions of phospholipases and their involvement in lipid metabolism. Overall, the investigation of PLA2G2D recombinant proteins is a promising avenue for advancing our understanding of lipid mediators in health and disease.
