Analytical Data
-
基因名
CD8 beta
- Application
-
别名
CD8B1; CD8 Antigen,Beta Polypeptide 1; T-cell surface glycoprotein CD8 beta chain
-
种属
Mouse
-
表达系统
E. coli
-
标签
N-His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P10300
-
表达区间
Leu22~Thr175
-
分子量
21kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CD8 beta is a glycoprotein that plays a crucial role in the immune response, particularly in the activation and function of cytotoxic T cells, which are essential for eliminating infected or malignant cells. The CD8 molecule consists of two subunits: CD8 alpha and CD8 beta, with the beta chain contributing to the overall stability and function of the CD8 complex. Research into CD8 beta recombinants has gained momentum due to their potential applications in immunotherapy, vaccine development, and understanding T cell signaling pathways. The ability to produce CD8 beta as a recombinant protein allows for detailed studies on its structure, interactions with major histocompatibility complex (MHC) molecules, and its role in T cell development and activation. Furthermore, understanding the distinct functions of the CD8 alpha and beta chains can help in designing more targeted immunotherapeutic strategies for diseases like cancer and viral infections. By elucidating the molecular mechanisms underlying CD8 beta's contribution to T cell responses, researchers aim to enhance the efficacy of immune-based therapies and improve patient outcomes. Overall, the investigation of CD8 beta recombination and function is pivotal in advancing our knowledge of T cell biology and developing innovative approaches for boosting the immune response in clinical settings.
