Analytical Data
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Gene name
FCRN-B2M
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简介
The FCGRT-B2M heterodimeric protein is a cell surface receptor that interacts with IgG and albumin and contributes to effective humoral immunity. FCGRT-B2M Heterodimer Protein, Rat (HEK293, C-His) is a recombinant protein dimer complex containing rat-derived FCGRT-B2M Heterodimer protein, expressed by HEK293 , with C-His labeled tag. FCGRT-B2M Heterodimer Protein, Rat (HEK293, C-His), has molecular weight of ~38-55 & 12 kDa, respectively.
- Application
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Biological Activity
Measured by its binding ability in a functional ELISA. When FCRN-B2M is immobilized at 2 µg/mL (100 µL/well), can bind Biotinylated Human lgG1. The ED50 for this effect is 109.3 ng/mL. Measured by its binding ability in a functional ELISA. When FCRN-B2M is immobilized at 2 µg/mL (100 µL/well), can bind Biotinylated Human lgG1, the ED50 for this effect is 109.3 ng/mL.
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Alternative Names
FCGRT-B2M Heterodimer Protein; IgG receptor FcRn large subunit p51; Beta-2-microglobulin
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Species
Rat
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Source
HEK293
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Tag
C-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P13599 (A23-S298)&P07151
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Expression Region
P13599 (A23-S298)&P07151 (I21-M119)
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Molecular Weight
38-55 & 12 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process











